Dexmedetomidine HCl

Catalog No.S2090 Batch:S209001

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Technical Data

Formula

C13H16N2.HCl

Molecular Weight 236.74 CAS No. 145108-58-3
Solubility (25°C)* In vitro DMSO 48 mg/mL (202.75 mM)
Ethanol 48 mg/mL (202.75 mM)
Water 20 mg/mL (84.48 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Dexmedetomidine HCl((+)-Medetomidine Hydrochloride) is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.
Targets
alpha-2 adrenoceptor [1]

Protocol (from reference)

Selleck's Dexmedetomidine HCl has been cited by 4 publications

PINK1-mediated mitophagy reduced inflammatory responses to Porphyromonas gingivalis in macrophages [ Oral Dis, 2022, 10.1111/odi.14286] PubMed: 35730318
A new high-content screening assay of the entire hepatitis B virus life cycle identifies novel antivirals [ JHEP Rep, 2021, 3(4):100296] PubMed: 34222850
Modulation of microglial phenotypes by dexmedetomidine through TREM2 reduces neuroinflammation in heatstroke [ Sci Rep, 2021, 11(1):13345] PubMed: 34172807
Dexmedetomidine-mediated regulation of miR-17-3p in H9C2 cells after hypoxia/reoxygenation injury [ Exp Ther Med, 2020, 20(2):917-925] PubMed: 32742334

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.