Receptor Bindingand Endocytosis PlasmaMembrane Fusion andUncoating EndoplasmicReticulum Virion Assembly MembranousWeb (-) RNA 3’ 5’ (-) RNA 3’ 5’ (+) RNA 5’ 3’ HCV RNA HCV IFN-α, IFN-β IFN-α andIFN-β IFN-R Transport and Release ProteinSynthesis Core RIG-I TLR3 IRF3 PKR eIF2α E2, IFN-stimulated Genes C p7 E1 E2 NS4B NS4A NS5B Translation and Polyprotein Processing RNA Replication NS2 P {{ board.text1 }} {{ board.text2 }} {{ board.text }} {{ board.text }} {{ board.text }} {{ board.text }} {{ group.title }} {{ text.text }} Notes: 1:Clickable 2:Unclickable P P