13 12 10 11 2 3 6 8 7 4 5 1 9 9 Fusion CD4 Co-receptor (CCR5 or CXCR4) Host Cell Budding Maturation ALIX,ESCRT-I,ESCRT-III Attachment Env HIV-1 Uncoating Reverse Transcription NuclearExport NuclearImport Tat Rev Vpu Vif RNA Pol II P-TEFb Translation Transcription Release AAA AAA AAA AAA AAA AAA AAA AAA AAA 5’LTR 3’LTR IntegrationLEDGF Accessory ViralProteins Assembly Pre-integration Complex Gag Gag Pol Translation Gag Gag Pol HIV Protease InhibitorsPepstatin ANelfinavirRitonavirLopinavir Pan-CXCR AntagonistReparixinSelective-CXCR AntagonistsPlerixafor (CXCR4)SB225002 (CXCR2)WZ811 (CXCR4) CCR AntagonistMaraviroc (CCR5)CCR AgonistZK756326 (CCR8) Integrase InhibitorsRaltegravirDolutegravirElvitegravirCabotegravirBictegravir Reverse TranscriptaseInhibitorsLamivudineEmtricitabineTenofovirZidovudineEfavirenz CRM1 InhibitorsSelinexorEltanexorKPT-185Verdinexor P {{ group.title }} {{ text.text }} {{ button.text }} {{ group.title }} {{ text.text }} Notes: 1:Clickable 2:Unclickable