NodalR I Angiogensis, Extracellular Matrix,Neurogenesis, Immunosuppression,Apoptosis Induction G1 Arrest Gonadal Growth,Embryo Differentiation,Placenta Formation, etc. Osteoblast Differentiation,Neurogenesis,Ventral Mesoderm Specification DNA DNA DNA DNA Transcription Factors,Co-activatorsand Co-repressors TAK1, MEKK1,DAXX/JNK Protein Synthesis Ubiquitin MediatedProteolysis DNA DNA Left-right Axis Determination,Mesoderm and Endoderm Nodal Activin A,B,C TGFβ1,2,3 TGFβ BMP2,4 BMPR II NodalR II Smad6/7 Smurf1/2 Smad7 PP2A Smad6/7 Pitx2 SP1 DP1 E2F4/5 p107 p15 Skp1 Rbx1 Cul1 SARA Id P {{ board.text }} {{ board.text2 }} {{ board.text }} {{ board.text }} {{ board.text }} {{ board.text }} {{ board.text }} {{ board.text }} {{ board.text }} {{ group.title }} {{ text.text }} {{ button.text }} {{ button.text }} {{ group.title }} {{ text.text }} Notes: 1:Clickable 2:Unclickable